Therapeutic and Clinical Models

Psilocybin with psychological support for treatment-resistant depression: six-month follow-up

This open‑label follow‑up of an initial feasibility study found that two doses of psilocybin administered with psychological support produced rapid, large, and sustained reductions in depressive symptoms among patients with treatment‑resistant depression, with effects lasting up to six months. The treatment was generally well tolerated, suggesting psilocybin‑assisted therapy may be a promising new approach for individuals who have not responded to conventional antidepressants.

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Music, Language, and the Brain

In Music, Language, and the Brain, Aniruddh Patel synthesizes research from cognitive neuroscience, psychology, linguistics, and musicology to argue that music and language share deep, structured neural and cognitive mechanisms, while also highlighting important differences in how the brain processes each.

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Musicophilia: Tales of Music and the Brain

In Musicophilia, neurologist Oliver Sacks explores the complex relationship between music and the human brain, presenting case histories of patients whose neurological conditions reveal how deeply music is intertwined with memory, emotion, identity, and perception. He shows that music can both reveal unexpected neural capacities and reveal the brain’s neuroplasticity, especially in the face of injury or disease.

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